High-Risk Pregnancy & PEARS: A Case Series

This case series reports nine successful pregnancies in women with Marfan or Loeys–Dietz syndromes who had previously undergone the PEARS aortic root support procedure. No aortic dissections or maternal deaths were observed.

Aortic dimensions remained stable throughout pregnancy and postpartum, and no hypertensive pregnancy disorders occurred. Both vaginal delivery and Caesarean section were safely undertaken.

Although small, the study suggests PEARS may be a promising pre-conception option for selected women with aortopathy.