Structural Cardiac Defect (Bicuspid Aortic Valve)
Malformed heart valves and associated aortic aneurysms are found in 1 in 1,000 population. It is possible that these patients also have errors in the Marfan syndrome gene fibrillin-1. Funding is required to study DNA samples from 100 such patients. This could determine how extensive the aortic surgery offered at the first operation should be, preventing multiple heart operations for some of these patients.
The funds raised would provide salary and laboratory consumables for 1 year.